Review Article

Stent Thrombosis: Incidence, Predictors and New Technologies

Table 5

A table to illustrate ongoing studies utilizing the results of platelet reactivity testing to assess outcomes following PCI.

StudyNumber of patientsPatient populationPlatelet reactivity valueAntiplatelet therapyPrimary endpoint

ARCTIC2,500Elective PCI<15%GPIIb/IIIa inhibitorsDeath, MI, Stroke, TVR, ST
DANTE442NSTEMIPRU > 240Clopidogrel 75 mg versus Clopidogrel 150 mgCardiovascular death, MI and TVR

ARCTIC: Monitored Adjusted Antiplatelet Treatment Versus a Common Antiplatelet Treatment for DES Implantation and Interruption Versus Continuation of Double Antiplatelet Therapy; DANTE: Dual Antiplatelet Therapy Tailored on the Extent of Platelet Inhibition; PCI: percutaneous coronary intervention; NSTEMI: Non-ST elevation myocardial infarction; GPIIb/IIIa: Glycoprotein IIb/IIIa inhibitor; MI: myocardial infarction; TVR: target vessel revascularization; ST: stent thrombosis; PRU: P2YC12 reaction unit.