The Role of Thrombophilia in Pregnancy

Table 1

Risk of VTE in inherited thrombophilia.

Thrombophilia	OR general population	Annual incidence of first VTE (%)	OR in pregnancy (95% CI)
AT deficiency	28.2	1.77	4.69 (1.30–16.96)
Protein C deficiency	24.1	1.52	4.76 (2.15–10.57)
Protein S deficiency	30.6	1.90	3.19 (1.48–6.86)
Factor V Leiden	7.5	0.49	Homozygous 34.4 (9.86–120.0); Heterozygous 8.32 (5.44–12.70)
Prothrombin gene mutation	5.2	0.34	Homozygous 26.36 (1.24–559.2); Heterozygous 6.80 (2.46–19.77)

CI: confidence interval.