Biomarkers of Coagulation and Fibrinolysis during Cemented Total Hip Arthroplasty with Pre- versus Postoperative Start of Thromboprophylaxis

Table 3

D-dimer (𝜇g·mL⁻¹). Time points are the day before surgery (1), after anaesthesia but before surgery (2), at the end of wound closure (3), at 6 hours after surgery (4), at the first day after surgery (5), and at 6 days after surgery (6). Values are mean ± standard deviation (SD) and 95% confidence interval (CI).

Time point	Preop. group	Postop. group	𝑃 value (ANOVA)
1	0.76±0.47 (0.02–1.51)	0.69±0.49 (−0.6–1.4)	0.965
2	0.75±0.56 (0.001–1.49)	0.79±0.87 (0.04–1.53)	0.965
3	3.71±1.22^a (2.97–4.46)	4.24±1.72^e (3.49–4.98)	0.965
4	5.15±2.19^b (4.40–5.89)	4.80±1.78^f (4.05–5.54)	0.965
5	2.61±1.15^c (1.87–3.35)	2.41±0.89^g (1.66–3.15)	0.965
6	1.97±0.42^d (1.19–2.76)	2.09±0.69^h (1.3–2.87)	0.965
𝑃 value (ANOVA)	<0.001	<0.001

 ^a𝑃<0.001; ^b𝑃<0.001; ^c𝑃=0.001; ^d𝑃=0.029; ^e𝑃<0.001; ^f𝑃<0.001; ^g𝑃=0.004; ^h𝑃=0.021, all in relation to time point 2.