Biomarkers of Coagulation and Fibrinolysis during Cemented Total Hip Arthroplasty with Pre- versus Postoperative Start of Thromboprophylaxis

Table 4

PAP (𝜇g·L⁻¹). Time points are the day before surgery (1), after anaesthesia but before surgery (2), at the end of wound closure (3), at 6 hours after surgery (4), at the first day after surgery (5), and at 6 days after surgery (6). Values are mean ± standard deviation (SD) and 95% confidence interval (CI).

Time point	Preop. group	Postop. group	𝑃 value (ANOVA)
1	627±153 (510–744)	511±172 (394–628)	0.110
2	616±149 (499–733)	478±106 (361–595)	0.110
3	917±257^a (800–1034)	936±255^e (819–1053)	0.110
4	1084±326^b (967–12019)	1033±204^f (916–1151)	0.110
5	588±124^c (471–705)	539±97^g (422–656)	0.110
6	846±90^d (729–963)	851±135^h (734–968)	0.110
𝑃 value time (ANOVA)	<0.001	<0.001

 ^a𝑃=0.002; ^b𝑃<0.001; ^c𝑃=0.756; ^d𝑃=0.013; ^e𝑃<0.001; ^f𝑃<0.001; ^g𝑃=0.429; ^h𝑃<0.001, all in relation to time point 2.