Venous Thromboembolism in Critically Ill Cirrhotic Patients: Practices of Prophylaxis and Incidence
Table 1
Characteristics of patients with and without liver cirrhosis.
Cirrhotic patients
Noncirrhotic patients
value
Age (years), mean ± SD
<0.0001
Male gender, (%)
37 (49.3)
498 (68.9)
0.0006
Body mass index (Kg/m2), mean ± SD
0.31
APACHE II score, mean ± SD
<0.0001
Admission GCS score, mean ± SD
0.19
Reason for ICU admission:
<0.0001
Respiratory, (%)
10 (13.3)
159 (22.0)
Cardiovascular, (%)
45 (60.0)
201 (27.8)
Neurological, (%)
1 (1.3)
56 (7.8)
Other medical, (%)
17 (22.7)
19 (2.6)
Nonoperative trauma, (%)
1 (1.3)
122 (16.9)
Postoperative, (%)
1 (1.3)
166 (23.0)
Bedridden before admission, (%)
54 (72.0)
340 (47.0)
<0.0001
Congestive heart failure, (%)
2 (2.6)
36 (5.0)
0.57
Previous stroke, (%)
4 (5.3)
102 (14.1)
0.03
Active malignancy, (%)
7 (9.3)
87 (12.0)
0.49
Femur fracture, (%)
1 (1.3)
51 (7.0)
0.08
Spinal cord injury, (%)
0 (0)
20 (2.8)
0.24
Previous history of VTE, (%)
0 (0)
12 (1.7)
0.62
Sepsis on admission, (%)
55 (73.3)
266 (36.8)
<0.0001
Mechanical ventilation on admission, (%)
62 (82.7)
625 (86.4)
0.37
Femoral central venous catheter, (%)
47 (62.7)
295 (40.8)
0.0003
Internal jugular or subclavian central venous catheter, (%)
50 (66.7)
475 (65.7)
0.87
Admission creatinine (mol/L), mean ± SD
0.002
Admission lactate (mmol/L), mean ± SD
0.004
Admission bilirubin (mol/L), mean ± SD
<0.0001
Admission platelet count/L, mean ± SD
<0.0001
Admission INR, mean ± SD
<0.0001
Admission PTT (seconds), mean ± SD
0.07
APACHE: Acute Physiology and Chronic Health Evaluation; GCS: Glasgow Coma Scale; ICU: intensive care unit; INR: International Normalized Ratio; PTT: partial thromboplastin time; SD: standard deviation.
