Research Article

Relationship of Acute Phase Reactants and Fat Accumulation during Treatment for Tuberculosis

Table 2

Changes in body composition during treatment.

Change in body compositionWeek 4Week 8Week 16Week 24P value ANOVA

Weight kg3.02 ± 0.81*,a4.94 ± 1.08a,b7.03 ± 0.97b,c8.59 ± 0.97c<0.0001
5.5%**9.0%12.8%15.6%
Fat-free mass kg0.93 ± 0.78a1.90 ± 0.95a, b3.02 ± 0.80b,*3.53 ± 0.78<0.0001
2.0%4.2%6.6%7.7%
Body cell mass kg0.02 ± 0.95a1.65 ± 1.02a,b4.00 ± 0.84b,*4.64 ± 0.93<0.0001
0.0%3.5%8.5%9.9%
Fat mass kg2.09 ± 0.52*,a3.04 ± 0.50a4.00 ± 0.59b5.05 ± 0.56b<0.0001
22.7%33.1%43.5%55.0%

*different at time point compared to baseline (P < 0.05); variance (±) is standard error.
**percent change is the ratio of the absolute increase at study week divided by the baseline value ×100.
a,b,c values with same superscript (“a” and “a”) are significantly different (adjusted P < 0.05) in pairwise comparisons.