Stratified Threshold Values of QuantiFERON Assay for Diagnosing Tuberculosis Infection in Immunocompromised Populations

Table 4

Proposed Immunocompetence-stratified positive criteria and borderline zone for whole blood T-cell assay (QuantiFERON-TB Gold).

Compromised host^a		Immunocompetent host (adult)
≥0.1^b	<0.1	≥0.3	0.1–0.3	<0.1
positive	Negative	postive	borderline	negative

Note: ^a: compromised hosts with impaired cell-mediated immunity and lymphocytopenia, such as patients receiving chronic immunosuppressive therapy, advanced malignant diseases, malnutrition, chronic renal failure on hemodialysis, HIV infection, and hospitalised elderly. ^b: IU/ml.