Research Article
Antimycobacterial Activities of Novel 5-(1H-1,2,3-Triazolyl)Methyl Oxazolidinones
Table 4
In vivo efficacy and observation at time of sacrifice.
| Compd. | Lungs | Spleen | Other remarks |
| Control | +++ | 6 enlarged; 1 very large | 2 with enlarged lymph nodes | INH | + | 1 slightly enlarged; 4 normal | n/a | 2l (306019) | ++ | 1 enlarged; 4 slightly enlarged | Large intestine distended full of feces and air | 1g (306027) | + | 1 slightly enlarged; 4 normal | Large intestine distended full of feces and air | PH-27 (306006) | + | normal | Large intestine distended full of feces and air |
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+++; highly infected. ++/+; hardly any infected. n/a; not applicable.
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