An IMS/ATP Assay for the Detection of Mycobacterium tuberculosis in Urine

Table 1

Summary results for detection of MTB in synthetic urine—blinded assays.

Replicate	Conc. (CFU/mL)	S : N at T1	S : N at any time point >T1	Average S : N (T1–T4)	Average S : N/T1	Send for confirmation
1	10^5	17.60	X	20.40	1.16	Yes
	10^5	12.69	X	18.45	1.45	Yes
	10^5	15.81	X	18.11	1.15	Yes
	10^4	2.14		2.07	0.97	No
	10^4	1.64	X	1.72	1.05	Yes
	10^4	2.30	X	4.09	1.78	Yes
	10^3	1.02		0.98	0.96	No
2	10^6	9.86	X	9.75	0.99	Yes
	10^6	12.99	X	12.83	0.99	Yes
	10^6	11.27	X	11.44	1.01	Yes
	10^5	4.00		3.76	0.94	No
	10^5	2.71		2.65	0.98	No
	10^5	3.61	X	3.58	0.99	Yes
	10^4	12.47	X	12.24	0.98	Yes
	10^4	15.43		15.05	0.98	No
3	10^6	4.45	X	4.60	1.03	Yes
	10^6	3.83		3.74	0.98	No
	10^6	3.72	X	3.75	1.01	Yes
	10^5	1.64	X	1.64	1.01	Yes
	10^5	1.16		1.11	0.95	No
	10^5	1.23		1.19	0.97	No
	10^4	1.11	X	1.09	0.98	Yes
	10^4	1.12		1.09	0.97	No
4	10^6	1.71	X	1.93	1.13	Yes
	10^6	8.57	X	14.65	1.71	Yes
	10^6	1.39	X	1.40	1.01	Yes
	10^6	5.62	X	7.20	1.28	Yes
	10^5	1.65	X	1.67	1.01	Yes