The Role of Foxp3-Expressing Regulatory T Cells and T Helpers in Immunopathogenesis of Multidrug Resistant Pulmonary Tuberculosis

Table 1

Relative amount of T helpers (CD3⁺CD4⁺CD25⁻) in peripheral blood of patients suffering from pulmonary tuberculosis, depending on the form of the disease and sensitivity of the causative agent to antitubercular drugs (%), Me (Q ₁–Q ₃).

Type of a researched patients	Relative amount of T helpers in the group	Relative amount of T helpers in the group
		depending on sensitivity of the causative
		agent to antitubercular drugs
		DS TB	MDR TB
Healthy donors	35,38 (32,74–38,74)
Patients with ITB	45,47	38,20	54,41
	(43,07–47,82)	(33,04–47,88)	(54,38–54,89)
	𝑝1=0,038		𝑝1=0,042
			𝑝4=0,036
Patients with DTB	31,61	23,90	39,38
	(29,33–34,41)	(16,84–26,66)	(24,57–48,75)
	𝑝1=0,042	𝑝1=0,043	𝑝1=0,049
	𝑝2=0,042	𝑝2=0,041	𝑝2=0,041
			𝑝4=0,048
Patients with FCTB	25,46	24,4	26,0
	(21,38–32,86)	(22,38–25,35)	(21,20–28,70)
	𝑝1=0,029	𝑝1=0,037	𝑝1=0,041
	𝑝2=0,048	𝑝2=0,045	𝑝2=0,028
	𝑝3=0,035		𝑝3=0,039

Note: 𝑝₁: the level of statistical significance of differences in comparison with the group of healthy donors; 𝑝₂: in ITB patients; 𝑝₃: in DTB patients; 𝑝₄: in DS TB patients.