The Role of Foxp3-Expressing Regulatory T Cells and T Helpers in Immunopathogenesis of Multidrug Resistant Pulmonary Tuberculosis

Table 2

Subpopulation composition of regulatory T cells of peripheral blood in patients suffering from pulmonary tuberculosis, depending on a clinical form of the disease (%), Me (Q ₁–Q ₃).

Groups of the researched patients	Relative content of regulatory T-cell subpopulations
	CD4^+CD25^+Foxp3^+	CD4^+CD25^−Foxp3^+	CD4^+CD25^+Foxp3^−
Healthy donors	2,63	5,12	25,45
	(2,00–3,29)	(4,76–9,75)	(22,30–27,60)
ITB patients	4,48	6,95	17,52
	(3,10–6,00)	(5,50–11,20)	(9,400–22,60)
	𝑝1=0,047		𝑝1=0,036
DTB patients	5,35	6,30	13,50
	(3,75–7,14)	(5,50–8,00)	(8,400–17,20)
	𝑝1=0,014		𝑝1=0,005
			𝑝2=0,026
FCTB patients	4,80	8,50	19,50
	(3,20–6,00)	(4,20–11,50)	(13,400–24,30)
	𝑝1=0,045	𝑝1=0,049	𝑝1=0,038
			𝑝2=0,047
			𝑝3=0,049

Note: 𝑝₁: the level of statistical significance of differences in comparison with the group of healthy donors; 𝑝₂: in ITB patients; 𝑝₃: in DTB patients.