Clinical Study
Adverse Reactions to Antituberculosis Drugs in Iranian Tuberculosis Patients
Table 1
Incidence, onset time
, and seriousness of anti-TB adverse drug reactions.
| | Type of ADRs | Minor ADRs (%) | Major ADRs (%) | Mean of onset time (range) days |
| | Gastrointestinal disorders | 114 (91.9) | 10 (8.1) | 19 (4–57) | | Liver dysfunction | 162 (80.6) | 39 (19.4) | 17 (12–68) | | Allergic reactions | 63 (73.3) | 23 (26.7) | 20 (6–45) | | Flu-like reactions | 76 (100) | 0 | 5 (1–9) | | Arthralgia | 29 (85.3) | 5 (14.7) | 36 (23–55) | | Hematologic disorders | 3 (42.8) | 4 (57.2) | 52 (29–81) | | Peripheral neuropathy | 14 (81.4) | 3 (17.6) | 48 (38–74) | | Renal impairment | 1 (20) | 4 (80) | 32 (27–41) | | Visual impairment | 1 (16.7) | 5 (83.3) | 46 (34–72) | | Ototoxicity | 1 (14.3) | 6 (85.7) | 33 (20–54) |
| | Total | 464 (82.4) | 99 (17.6) | 19 (4–81) |
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It was from initiation of treatment. (It was the time that ADRs were found, not the exact time it happened.)
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