Performance of Tuberculin Skin Test Measured against Interferon Gamma Release Assay as Reference Standard in Children

Table 1

Characteristics of studies reporting on children with results on tuberculin skin test and interferon gamma release assay and information on BCG immunisation status (TB: tuberculosis).

Study reference	Country	Setting	Reason for testing	Age	Children with BCG immunisation	Children without BCG immunisation	Active TB (%)
Dogra et al. 2007 [4]^a	India	Rural Medical School	Suspect cases or contacts	Median: 6.0 years (range 1 to 12)	86	19	10.5
Chun et al. 2008 [5]	South Korea	Municipal Children’s Hospital	Close and casual contacts and cases	Median 3.2 years (range 0–15.8)	145	—	3.0
Taylor et al. 2008 [6]	United Kingdom	Municipal Hospital	Contacts	Mean 10 years (range 4 to 16)	45	—	10.9 (suspected)
Nicol et al. 2009 [7]	South Africa	Semirural population	Suspected tuberculosis or contacts	Median 1.5 years (IQR 1.1 to 2)	214	—	26.8
Bakir et al. 2009 [1]	Turkey	Municipal clinics	Contacts	Median 7 years (IQR 3 to 11)	652	209	1.3
Soon et al. 2010 [8]	South Korea	Municipal Hospital	Contacts	Median 5 years	26	—	21.2
Stefan et al. 2010 [9]	South Africa	Municipal Hospital	Children newly diagnosed with cancer	Median 7 years (range 0.1 to 15)	29	—	2.9
Méndez-; Echevarría et al. 2011 [10]	Spain	Municipal Hospitals	Immigrants from endemic areas, contacts, and cases	Mean age 4.73 (range 0.1 to 15)	213	246	14.8
Kasambira et al. 2011 [11]	South Africa	Rural clinics, District Hospital	Contacts	Median age 6 years (IQR 3 to 9)	236	—	19.0
Moyo et al. 2011 [12]	South Africa	Rural district	Contacts and suspected cases	Median 1.9 years (range 0.75 to 2.83)	376	—	13.1
Nkurunungi et al. 2012 [13]	Uganda	Municipal Hospital	Population based screening	5 years	300	—	0.3

aNumbers in brackets refer to the number of the reference in References of the paper.