Multiplex Analysis of Pro- or Anti-Inflammatory Serum Cytokines and Chemokines in relation to Gender and Age among Tanzanian Tuberculous Lymphadenitis Patients
Table 5
Differences in the serum cytokine levels in the adult Tanzanian patients based on gender and mycobacterial culture from lymph nodes.
Cytokine (pg/mL)
Male () Median (range)
Female () Median (range)
value
Culture positive () Median (range)
Culture negative () Median (range)
value
IFN-
0.0 (0–42.8)
0.0 (0–30.9)
0.98
0.0 (0–22.4)
0.0 (0–42.8)
0.383
TNF-
3.2 (0–352.5)
11.8 (0–73)
0.15
8.4 (0.5–352.5)
12.4 (0–72.9)
0.874
GM-CSF
35.2 (0–507)
55.1 (0–457)
0.96
35.2 (0–506.9)
34.5 (0–457.7)
0.864
IL-1
72.6 (0–1338)
5.7 (0–6305)
0.51
0.0 (0–1338.8)
66.5 (0–6305.4)
0.746
IL-2
0.0 (0–28)
0.0 (0–19.8)
0.31
0.0 (0–28.2)
0.0 (0–19.8)
0.193
IL-4
0 (0–9.5)
0 (0–18)
0.30
0.0 (0–6.8)
0.0 (0–18.5)
0.360
IL-5
1.5 (0–10)
0.75 (0–6.4)
0.16
1.0 (0–8.1)
1.0 (0–10.0)
0.465
IL-6
46.4 (0–18979)
55.5 (0–25781)
0.80
46.4 (0–18979.1)
55.6 (0–25781.5)
0.825
IL-8
362 (0–27670)
419 (0–386577)
0.70
638.2 (0–27670.3)
366.4 (0–386578.0)
0.486
IL-10
0.0 (0–29)
0.0 (0–22)
0.96
0.0 (0–29.3)
0.0 (0–22.8)
0.513
IL-12
0 (0–20.7)
0.1 (0–37)
0.03
0.3 (0–20.7)
0.0 (0–37.8)
0.029
IL-15
0.0 (0–61)
0.0 (0–25)
0.77
0.6 (0–21.1)
0.0 (0–61.4)
0.223
IL-17
0 (0–134)
0
0.04
0.0 (0–26.1)
0.0 (0–133.7)
0.638
value for difference between males and females and value for difference between culture positive and culture negative TB patients.
