Research Article

Tuberculosis Case Finding Cascade and Treatment Outcomes among Male Inmates in Two Prisons in Zimbabwe

Table 3

Factors associated with tuberculosis treatment outcomes among adult inmates admitted at Harare Central Prison and Chikurubi Maximum Prison, Zimbabwe, 2015-2018.

CharacteristicsTotalUnfavourable outcome, (%)Unadjusted RR (95% CI)Adjusted RR (95% CI) value

Total28071 (25.4)
Age groups in years
 18-296317 (27.0)1.62 (0.70-3.73)1.56 (0.67-3.62)0.298
 30-4416841 (24.4)1.46 (0.67-3.18)1.48 (0.68-3.22)0.328
 45-59366 (16.7)11
 ≥60137 (53.9)3.23 (1.33-7.84)2.80 (1.1-6.9)0.030
Residence
 Urban15140 (26.5)1.08 (0.72-1.62)1.19 (0.78-1.81)0.420
 Rural12230 (24.6)11
 Not recorded71 (14.3)0.58 (0.09-3.66)0.75 (0.13-4.29)0.748
Site of TB
 Pulmonary21249 (23.1)11
 Extrapulmonary153 (20.0)0.87 (0.31-2.45)0.77 (0.26-2.27)0.637
 Not recorded5319 (35.9)1.55 (1.00-2.39)1.41 (0.82-2.4)0.210
Classification by sputum status
 Bacteriologically confirmed12122 (18.2)1
 Clinically diagnosed13539 (28.9)1.59 (1.00-2.52)1.36 (0.79-2.32)0.265
 Not recorded2410 (41.7)2.29 (1.25-4.19)1.99 (1.04-3.81)0.038
Classification by history of TB treatment
 New22756 (24.7)11
 Previously treated4914 (28.6)1.16 (0.70-1.90)1.07 (0.66-1.72)0.793
 Not recorded41 (25.0)1.01 (0.18-5.61)0.87 (0.10-7.8)0.901
HIV and ART status
 HIV negative9625 (26.0)11
 HIV positive and on ART14436 (25.0)0.96 (0.62-1.49)1.04 (0.66-1.64)0.871
 HIV positive and not on ART297 (24.1)0.93 (0.45-1.92)0.88 (0.40-1.91)0.739
 HIV positive and ART status unknown72 (28.6)1.10 (0.32-3.71)1.22 (0.39-3.83)0.734
 HIV status unknown41 (25.0)0.96 (0.17-5.42)1.34 (0.15-12.2)0.794

RR: relative risk; CI: confidence interval; TB: tuberculosis; ART: antiretroviral therapy. Unfavourable outcomes include death, loss to follow-up, and “outcome not evaluated.” Adjusted RR is based on the multivariable model (log-binomial regression), and all exposure variables were included in the model. values are from multivariable analysis, and values < 0.05 are highlighted in bold.