Research Article

New Role for L-Arginine in Regulation of Inducible Nitric-Oxide-Synthase-Derived Superoxide Anion Production in Raw 264.7 Macrophages

Figure 4

Nitrotyrosine formation in (a) RAW 264.7 cells, (b) RAW 264.7 cells stimulated with LPS, (c) LPS-stimulated RAW 264.7 cells treated with L-NAME (25 μM), (d) iNOS−/− RAW 264.7 cells, (e) iNOS−/− RAW 264.7 cells stimulated with LPS, and (f) RAW 264.7 cells transfected with negative control plasmid stimulated with LPS. Cells were incubated in the presence of DMEM media supplemented with 400 μM of L-arginine.
321979.fig.004