Midkine in Inflammation

Table 2

Overview of MK receptors.

Receptor family	MK receptor	Function	Publication
PTP	PTP𝜁	Migration of embryonic neurons	Maeda et al. 1999 [45]
		Migration of UMR106 osteoblast-like cells	Qi et al. 2001 [46]
		Survival of embryonic neurons	Sakaguchi et al. 2003 [47]
LRP	LRP-1	Survival of embryonic neurons	Muramatsu et al. 2000 [48]
		Prevention of hypoxic injury in mouse embryonic stem cells	Lee et al. 2011 [49]
	megalin/brushin		Muramatsu et al. 2000 [48]
	LRP-6		Muramatsu et al. 2000 [48], Muramatsu et al. 2004 [51]
	apoE receptor-2		Muramatsu et al. 2000 [48]
Integrins	α 4β 1	Migration of UMR106 osteoblast-like cells	Muramatsu et al. 2004 [51]
	α 6β 1	Neurite outgrowth of embryonic neurons	Muramatsu et al. 2004 [51], Huang et al. 2008 [52]
Notch	notch2	Epithelial mesenchymal transition of immortalized HaCaT keratinocytes	Huang et al. 2008 [52]
		Epithelial mesenchymal transition and chemoresistance in pancreatic ductal adenocarcinoma cells	Güngör et al. 2011 [53]
Receptor tyrosine kinase	ALK	Growth of SW-13 cells in soft agar	Stoica et al. 2007 [7]
Carbohydrates	Neuroglycan C	Process elongation of oligodendrocyte precursor-like cells	Ichihara-Tanaka et al. 2006 [54]
	Heparan sulfate trisulfated units		Kaneda et al. 1996 [55],; Ueoka et al. 2000 [56],; Zou et al. 2003 [57]
	Chondroitin sulfate E units		Ueoka et al. 2000 [56],; Zou et al. 2003 [57]
	Syndecan-1		Mitsiadis et al. 1995 [58]
	Syndecan-3		Mitsiadis et al. 1995 [58], Nakanishi et al. 1997 [59]
	Glypican-2		Kurosawa et al. 2001 [60]