In Vivo Expression of Interleukin-37 Reduces Local and Systemic Inflammation in Concanavalin A-Induced Hepatitis

Figure 3

LPS-induced serum cytokines in mice expressing IL-37. Tail vein injected C57/Bl6 mice (with or without IL-1F7b plasmid-DNA) were challenged with LPS (10 μg) intraperintoneally (𝑛 = 7–9). After 2 hrs the mice were sacrificed and serum cytokines were measured by a multiarray cytokine assay as described.