In Vivo Expression of Interleukin-37 Reduces Local and Systemic Inflammation in Concanavalin A-Induced Hepatitis
Figure 6
Histological hepatitis score and IL-6 protein expression in the liver of mice after ConA-induced hepatitis. Areas of portal inflammation (a and b) and necrosis (c and d) in ConA-induced hepatitis in control mice (histology of IL-37-expressing mice not shown). Histological hepatitis score analyzed for IL-37 expressing mice (open bars) and control mice (closed bars) (e). IL-6 in liver lysate was analyzed by multiarray cytokine assay and is expressed as pg/mg total protein in liver lysate (f).
