Influence of the Flexible Liposomes on the Skin Deposition of a Hydrophilic Model Drug, Carboxyfluorescein: Dependency on Their Composition

Table 2

Amounts of CF (expressed as cumulative % of dose applied, 𝑛=3) in the different layers of rat skin after 6 hours of nonocclusive incubation.

Code	SC	Stripped Skin	Receptor	Total
CF-CL	0.93±0.45	0.12±0.05	0.03±0.01	1.08±0.17
CF-FL1	3.61±0.23	0.55±0.17	0.29±0.05	4.45±0.23
CF-FL2	4.12±0.19	0.31±0.05	0.18±0.03	4.61±0.15
CF-FL3	7.36±0.13	0.34±0.13	0.14±0.02	7.85±0.09
PBS control	0.35±0.11	0.03±0.01	not detectable	0.38±0.04