Mitochondrial Electron Transport Chain in Heavy Metal-Induced Neurotoxicity: Effects of Cadmium, Mercury, and Copper

Table 2

Resting respiration rates (%) of PC12 cells after different time of incubation with increasing concentration of Hg²⁺, Cd²⁺, or Cu²⁺.

Time (h)	Control	[Hg^2+], μM		[Cd^2+], μM				[Cu^2+], μM
		10	50	10	50	100	500	10	50	100	500
3			*			*	*
5						*
24			*		*	*	0*
48		*									*

Rate of oxygen uptake is presented in percentage of the maximal (fully uncoupled) respiration of the control cells. Mean ± SE; independent experiments; * compared to untreated control.