Characterization of the Immune Response Induced by a Commercially Available Inactivated Bluetongue Virus Serotype 1 Vaccine in Sheep
Figure 1
(a) Antibody response in serum samples (mean optical density ± SD) measured by ELISA during the experiment. The threshold below which a response was considered negative was defined as 15% of the positive control optical density. Thus, samples with an optical density > 0.252 were considered positive. The mean value after boost vaccination was significantly different from that after challenge (**P ≤ 0.05; Mann-Whitney U test for nonparametric distributions). (b) Individual measurements of antibody response. Abbreviations: V, day of first vaccination; DFV, day after first vaccination; BV, day of boost vaccination; C, day of challenge.
