Table 1: Diagnostic criteria and degrees of diagnostic certainty for neurocysticercosis (Modified from: [35]).

Diagnostic criteria

Absolute
(i) Histologic demonstration of the parasite from biopsy of a brain or spinal cord lesion.
(ii) Evidence of cystic lesions showing the scolex on neuroimaging studies.
(iii) Direct visualization of subretinal parasites by fundoscopic examination.
(iv) Spontaneous resolution of small single enhancing lesions.

Major
(i) Evidence of lesions highly suggestive of neurocysticercosis on neuroimaging studies.
(ii) Positive serum immunoblot for the detection of anticysticercal antibodies.
(iii) Resolution of intracranial cystic lesions after therapy with albendazole or praziquantel.

Minor
(i) Evidence of lesions suggestive of neurocysticercosis on neuroimaging studies.
(ii) Presence of clinical manifestations suggestive of neurocysticercosis.
(iii) Positive CSF ELISA for detection of anticysticercal antibodies or cysticercal antigens.
(iv) Evidence of cysticercosis outside the central nervous system.

Epidemiologic
(i) Individuals coming from or living in an area where cysticercosis is endemic.
(ii) History of frequent travel to disease-endemic areas.
(iii) Evidence of household a contact with T. solium infection.

Degrees of diagnostic certainty

Definitive
(i) Presence of one absolute criterion.
(ii) Presence of two major plus one minor or one epidemiologic criteria.

Probable
(i) Presence of one major plus two minor criteria.
(ii) Presence of one major plus one minor and one epidemiologic criteria.
(iii) Presence of three minor plus one epidemiologic criteria.