Research Article

Tuberculous Meningitis in Adults: A Review of 160 Cases

Table 1

Clinical and laboratory characteristics of TBM cases.

𝑛 (%)

Headache138 (86.3)
Fever110 (69.2)
Nausea vomiting102 (63.8)
Lack of appetite weakness65 (40.6)
Change in personality44 (27.5)
Weight loss42 (26.3)
Night sweats37 (23.1)
Stiff neck141 (88.1)
Meningeal irritation findings59 (36.9)
Blurred consciousness95 (59.4)
Cranial nerve palsy38 (23.8)
Coma33 (20.6)
Convulsions25 (15.6)
Plegia/paresis24 (15)
Peripheral WBC count
( 𝑛 1 3 1 )
normal97 (74)
abnormal*34 (26)
CSF WBC count/mm3
( 𝑛 1 4 8 )
<10047 (31.8)
100–50086 (58.1)
>50015 (10.1)
CSF/blood glucose ratio
( 𝑛 1 4 8 )
<0.60140 (94.6)
≤0.3081 (54.7)
CSF protein level mg/dL
( 𝑛 1 4 8 )
<4013 (8.8)
40–15074 (50)
>15061 (41.2)
Culture positivity in CSF59 (39.9)
Cranial CT or MRI
𝑛 1 3 4
Tuberculoma49 (36.6)
Basal meningitis36 (26.9)
Leptomeningeal palsy34 (25.4)
Hydrocephalus28 (20.9)
Edema16 (11.9)
Ischemia-infarct12 (8.9)
Abscess5 (3.7)
Arachnoiditis3 (2.2)
Normal30 (22.4)

Normal 4000–10000/mm3.
Abnormal* >10000/mm3.