Research Article

The Effect of an Enamel Matrix Derivative (Emdogain) Combined with Bone Ceramic on Bone Formation in Mandibular Defects: A Histomorphometric and Immunohistochemical Study in the Canine

Table 1

Mean percentage (± SDs) of tissue areas for each experimental group.

Experimental groupTissue type
Total bone formationLamellar bone formationWoven bone formationFibrous connective tissue

EMD/BC with membrane6 a a a a
EMD/BC without membrane6 a b a b
Membrane only6 b c a,b c
Control6 c c b c

a,b,cDifferent superscript letters indicate statistically significant differences (). EMD/BC = Combination of Emdogain with BC (biphasic calcium phosphate, i.e., TCP + HA).