Clinical Manifestations Vary with Different Age Spectrums in Infants with Kawasaki Disease

Table 1

Incidence and clinical manifestations.

Variable	Group 1 (𝑛=30)	Group 2 (𝑛=35)	Group 3 (𝑛=80)	𝑃 value
				Group 1; versus group 2	Group 1; versus group 3	Group 2; versus group 3
Days between disease onset to diagnosis, mean ± SD	8.5±3.7	6.3±2.5	6.7±3.1	0.006^†	0.010^†	0.506
M/F	24/6	26/9	45/35	0.803	0.038^†	0.105
Fulfill diagnosis criteria in 10 days, 𝑛(%)	11 (37%)	23 (66%)	64 (80%)	0.037^†	<0.001^†	0.160
Incomplete Kawasaki disease, 𝑛 (%)	19 (63%)	12 (34%)	16 (20%)	0.037^†	<0.001^†	0.160
Major criteria
Fever > 5 days, 𝑛 (%)	30 (100%)	33 (94%)	75 (94%)	0.945	0.375	0.754
Bilateral bulbar conjunctiva injection, 𝑛 (%)	25 (83%)	35 (100%)	75 (94%)	0.017^†	0.187	0.310
Change in mucosa of oropharynx, 𝑛 (%)	26 (87%)	32 (91%)	73 (91%)	0.695	0.721	0.743
Change of the extremities, 𝑛 (%)	12 (40%)	18 (51%)	40 (50%)	0.502	0.471	0.951
Skin rash, 𝑛 (%)	27 (90%)	32 (91%)	73 (91%)	1.00	0.866	0.743
Lymphadenopathy,; 𝑛 (%)	4 (13%)	12 (34%)	51 (64%)	0.096	<0.001^†	0.007^†
Other clinical manifestations
Upper respiratory tract infection, 𝑛 (%)	18 (60%)	21 (60%)	35 (44%)	0.800	0.192	0.161
Diarrhea/vomiting,; 𝑛 (%)	12 (40%)	14 (40%)	19 (24%)	0.800	0.147	0.121
Sterile pyuria, 𝑛 (%)	14 (40%)	14 (40%)	16 (20%)	0.772	0.011^†	0.044^†
Perianal desquamation, 𝑛 (%)	7 (23%)	2 (6%)	16 (20%)	0.096	0.905	0.097

^†Statistical significance.