Research Article
Antioxidants for Preventing Preeclampsia: A Systematic Review
Table 2
Fetal outcomes meta-analysis and heterogeneity results. Comparison: antioxidants versus placebo.
| Outcome | Studies | Population size | Pooled RR | 95% CI | value | Heterogeneity tests | Chi² value | | Tau² |
| Preterm birth | 13 | 21,166 | 1.03 | 0.94–1.14 | 0.51 | 0.05 | 43.9% | 0.01 | Small for gestational age <3rd centile | 2 | 11,634 | 0.85 | 0.56–1.30 | 0.46 | 0.12 | 57.9% | 0.06 | Small for gestational age <5th centile | 2 | 5,320 | 1.06 | 0.88–1.28 | 0.54 | 0.21 | 37.6% | 0.01 | Small for gestational age <10th centile | 8 | 9,672 | 0.92 | 0.80–1.05 | 0.22 | 0.06 | 49.2% | 0.02 | Miscarriage or stillbirth | 8 | 9,209 | 1.17 | 0.79–1.74 | 0.44 | 0.14 | 35.6% | 0.11 | Neonatal death | 8 | 19,135 | 0.79 | 0.54–1.17 | 0.24 | 0.88 | 0.0% | 0.00 |
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