Review Article

Distribution of Extrasynaptic NMDA Receptors on Neurons

Figure 5

Localization of NMDAR (a–e) and PSD-95 (f–k) antibody labeling mossy terminal glomeruli in the cerebellar granular layer. The pan1 NMDAR antibody is shown here but this was corroborated using 3 more NR1 and 1 NR2A/B antibodies (see Petralia et al. [36] for details). Labeling is limited mainly to synapses (arrows: between the mossy terminal (mt) and dendrite processes from granule cells) and attachment plaques (arrowheads: mainly between granule cell dendrite processes). Scale bar is 200 nm. Reprinted from parts of Figures 2 and 3 from Petralia et al. [36].
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