Traditional Medicinal Herbs and Food Plants Have the Potential to Inhibit Key Carbohydrate Hydrolyzing Enzymes In Vitro and Reduce Postprandial Blood Glucose Peaks In Vivo

Table 3

Blood glucose level in glycogen-loaded mouse after oral administration of AM, FF, and MC extracts.

Samples	Without extract			Blood glucose concentration (mg/dl)^a
		Crude methanol extract		Crude water extract		Ethylacetate fraction
		1 g/kg	2 g/kg	1 g/kg	2 g/kg	1 g/kg	2 g/kg
AM	375±38	272±19^∗; [−27.5]	191±14^∗; [−49.1]	266±21^∗; [−29.1]	196±13^∗; [−47.8]	185±17^∗; [−50.1]	152±19^∗; [−59.4]
FF	386±35	368±37; [−4.7]	352±32; [−8.8]	369±35; [−4.4]	349±22; [−9.6]	367±39; [−4.9]	359±29; [−7.0]
MC	379±48	219±29^∗; [−42.2]	171±39^∗; [−54.9]	253±26^∗; [−33.2]	176±13^∗; [−53.6]	162±11^∗; [−57.3]	136±15^∗; [−64.1]
Acarbose	172±19^∗[−55.1]

^aResults are expressed as means ± S.E.M of seven observations in each group. (% inhibition compared to respective control (without extracts added)).
*Values significantly different (𝑃<0.05) from the control in each group (before extract ingested). The average of blood glucose level without administration of extracts or glycogen was 157±11 mg/dL. The dose of acarbose was 400 mg/kg.