LDL-Apheresis: Technical and Clinical Aspects

Table 5

Clinical results with the HELP-LDL apheresis system (B. Braun, Germany) (literature overview).

Year	Authors	Diagnosis	HELP patients (𝑛)	Drop out	Therapy duration (years)	Side effects (%)	Outcome
1987	Eisenhauer et al. [18]	FH, CHD	13	—	0.5–1.3	?	13 improved
1988	Thiery et al. [19]	FH, CHD	7	—	0.5–1.0	3.2	7 improved
1991	Seidel et al. [20]	FH, CHD	51	5	1.0	2.9	46 improved
1993	Bosch et al. [21]	FH, CHD ESRD	3 (HD)	—	1.5	13.0	3 improved
1994	Schuff-Werner et al. [22]	FH, CHD	51	12	2.0	2.8	39 improved
1997	Jaeger et al. [23]	FH, CHD HTX	15	—	3.6	—	5 improved
1998	Mellwig et al. [24]	FH, CHD	9	—	?	—	8 improved
1999	Donner et al. [25]	FH	4	—	?	?	4 improved
2000	Schettler et al. [26]	FH, CHD	18	—	>0.5	—	18 improved
2001	Moriarty et al. [27]	FH	4	—	0.5	—	4 improved
2008	Wang [28]	FH, CHD	22	—	1.0	—	22 improved

ESRD: end-stage renal disease and HTX: heart transplantation.