Antioxidant Action of Mangrove Polyphenols against Gastric Damage Induced by Absolute Ethanol and Ischemia-Reperfusion in the Rat
Table 3
Effect of RM on the antioxidant compounds and enzymes in ischemia-reperfusion-induced gastric ulcer in rats.
Treatments
Dose (mg kg−1)
GSH (nmol mg of protein−1)
SOD (U mg of protein−1)
Saline
10 (mL kg−1)
13.39 ± 1.923
10.61 ± 0.304
Sham
—
23.26 ± 0.802**
13.42 ± 1.987
Lansoprazole
30
18. 91 ± 2.036
25.14 ± 2.363***
RM
0.5
20.93 ± 1.535*
18.48 ± 1.882*
Treatments
Dose (mg kg−1)
GPx (nmol min−1 mg of protein)
GR (nmol min−1 mg of protein−1)
Saline
10 (mL kg−1)
13.58 ± 1.011
18.00 ± 1.015
Sham
—
15.60 ± 1.612
18.44 ± 0.888
Lansoprazole
30
13.47 ± 0.967
18.94 ± 0.705
RM
0.5
21.96 ± 1.917**
26.86 ± 2.341**
Treatments
Dose (mg kg−1)
LPO (nmol TBARS−1 mg of protein−1)
MPO (U mg of protein−1)
Saline
10 (mL kg−1)
2.43 ± 0.111
2.43 ± 0.127
Sham
—
1.77 ± 0.117*
1.25 ± 0.168***
Lansoprazole
30
2.23 ± 0.176
2.21 ± 0.079
RM
0.5
1.758 ± 0.141*
1.86 ± 0.128*
The results are expressed as mean ± s.e.m. (), statistical significance was determined by one-way analysis of variance (ANOVA) followed by Dunnett’s post hoc t test, (*, **, and ***).
