Research Article

Prognostic Value of Hepatocyte Growth Factor, Syndecan-1, and Osteopontin in Multiple Myeloma and Monoclonal Gammopathy of Undetermined Significance

Figure 1

Comparison of serum levels of hepatocyte growth factor (HGF) in different phases of multiple myeloma and in monoclonal gammopathy of undetermined significance. Vertical axis: serum levels of hepatocyte growth factor (HGF, pg/mL). Horizontal axis: (A) multiple myeloma at the time of diagnosis, (B) multiple myeloma (MM) in relapse/progression, (C) remission phase multiple myeloma, (D) monoclonal gammopathy of undetermined significance (MGUS). The differences between active phase MM (A versus B) and remission phase myeloma and MGUS (C and D) were not statistically different. Significant differences were found between MM at the time of diagnosis and remission phase myeloma (A versus C; M 2001,0 versus 1049,0 pg/mL, 𝑃 < 0 , 0 0 0 1 ), MM at the time of diagnosis and MGUS (A versus D; 2001,0 versus 1228,0 pg/mL, 𝑃 < 0 , 0 0 0 1 ), MM in relapse/progression and remission phase MM (B versus C; M 1370,0 versus 1049,0 pg/mL, 𝑃 < 0 , 0 0 0 1 ), and MM in relapse/progression and MGUS (B versus D; 1370,0 versus 1228,0 pg/mL, 𝑃 = 0 , 0 0 0 2 ).
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