The Involvement of Angiotensin Type 1  and Type 2  Receptors in Estrogen-Induced Cell Proliferation and Vascular Endothelial Growth Factor Expression in the Rat Anterior Pituitary

<table>The influence of AT1 receptor antagonist losartan (L), AT2 receptor antagonist PD123319 (PD), and ACE inhibitor captopril (C) on diethylstilboestrol- (DES-) induced increase in number of PCNA immunopositive cells in anterior pituitary of rats. X ± SEM; <svg height="15.4375" id="M2" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 65.099998 15.4375" width="65.099998" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,15.4375)">
<g transform="translate(72,-59.65)">
<text transform="matrix(1,0,0,-1,-69.87,67.83)">
<tspan style="font-size: 8.75px; " x="0" y="0">∗</tspan>
</text>
<text transform="matrix(1,0,0,-1,-64.79,61.87)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑃</tspan>
<tspan style="font-size: 12.50px; " x="10.9" y="-0.95999998">&lt;</tspan>
<tspan style="font-size: 12.50px; " x="22.927885" y="-0.95999998">0</tspan>
<tspan style="font-size: 12.50px; " x="29.179386" y="-0.95999998">.</tspan>
<tspan style="font-size: 12.50px; " x="32.305138" y="-0.95999998">0</tspan>
<tspan style="font-size: 12.50px; " x="38.556637" y="-0.95999998">5</tspan>
</text>
</g>
</g>
</svg> versus C (DES−, control DES-untreated group), <svg height="15.8375" id="M3" style="vertical-align:-3.13504pt" version="1.1" viewbox="0 0 70.8125 15.8375" width="70.8125" xmlns="http://www.w3.org/2000/svg">
<g transform="matrix(1.25,0,0,-1.25,0,15.8375)">
<g transform="translate(72,-59.33)">
<text transform="matrix(1,0,0,-1,-69.87,67.83)">
<tspan style="font-size: 8.75px; " x="0" y="0">∗</tspan>
<tspan style="font-size: 8.75px; " x="4.5772958" y="0">∗</tspan>
</text>
<text transform="matrix(1,0,0,-1,-60.21,62.51)">
<tspan style="font-size: 12.50px; " x="0" y="0">𝑃</tspan>
<tspan style="font-size: 12.50px; " x="10.890113" y="0">&lt;</tspan>
<tspan style="font-size: 12.50px; " x="22.930502" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="29.182001" y="0">.</tspan>
<tspan style="font-size: 12.50px; " x="32.307751" y="0">0</tspan>
<tspan style="font-size: 12.50px; " x="38.559254" y="0">5</tspan>
</text>
</g>
</g>
</svg> versus C (DES+, control DES-treated group), LI: labeling index (the number of PCNA-immunopositive cells per 1000 randomly scattered cells of anterior pituitary).</table>

The Scientific World Journal

fig1

Figure 1

Figure 1: The Involvement of Angiotensin Type 1  and Type 2  Receptors in Estrogen-Induced Cell Proliferation and Vascular Endothelial Growth Factor Expression in the Rat Anterior Pituitary 

Figure 1 | The Involvement of Angiotensin Type 1  and Type 2  Receptors in Estrogen-Induced Cell Proliferation and Vascular Endothelial Growth Factor Expression in the Rat Anterior Pituitary 