The Involvement of Angiotensin Type 1 and Type 2 Receptors in Estrogen-Induced Cell Proliferation and Vascular Endothelial Growth Factor Expression in the Rat Anterior Pituitary
Figure 3
The influence of AT1 receptor antagonist losartan (L), AT2 receptor antagonist PD123319 (PD) and ACE inhibitor captopril (C) on diethylstilboestrol- (DES-) induced increase in number of vascular endothelial growth factor (VEGF) immunopositive cells in anterior pituitary of rats. X Β± SEM; versus C (DESβ, control DES-untreated group), versus C (DES+, control DES-treated group). pale gray: weak VEGF immunoreactivity; dark gray: medium VEGF immunoreactivity; black: strong VEGF immunoreactivity.