Antitumor and Immunopotentiating Activity of Polysaccharide PST001 Isolated from the Seed Kernel of Tamarindus indica: An In Vivo Study in Mice

Table 9

Effect of PST001 on biochemical parameters in mice.

	Normal range	Control	100 mg/kg PST001	200 mg/kg PST001	400 mg/kg PST001
(1) Blood Urea (mg%)	5–40	30 ± 2.12	34 ± 0.70***	25 ± 0.98***	29 ± 1.13^ns
(2) Serum Creatinine (mg%)	0–1.2	1.1±0.02	1.0±0.14^ns	0.7±0.07^∗∗∗	0.8±0.09^∗∗∗
(3) SGOT (IU/L)	8–40	47 ± 1.41	28 ± 0.70***	30 ± 0.42***	31 ± 0.84***
(4) SGPT (IU/L)	5–35	10 ± 1.27	13 ± 0.84***	11 ± 0.70^ns	9 ± 0.42^ns

Data were expressed as mean ± SD (𝑛=6) on day 15 of the experiment. Statistically significant differences are at *𝑃<0.05, **𝑃<0.01, ***𝑃<0.001; ns is non-significant, when compared between control, 100 mg/kg PST001, 200 mg/kg PST001, and 400 mg/kg PST001 using Tukey’s multiple comparison’s test (Graph Pad Prism 4.0). SGOT: Serum Glutamate Oxaloacetate Transaminase, SGPT: Serum Glutamate Pyruvate Transaminase.