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| Patient number and DSM-IV diagnosis (Sex, Age) | Stage of treatment-resistant depression | Prior/concomitant medication (dosage: mg/day) | Follow-up visit (weeks) | Pramipexole dosage at endpoint (mg/day) | HDRS-21 decrease at endpoint (%) | Adverse events (reason for dropping out) |
|
| (1) BPII (M, 52) | Stage III | Amoxapine (125)
Lithium (800) | 12 | 1 | 100 | None |
| | | |
| (2) MDD, dysthymic disorder (F, 46) | Stage III | Fluvoxamine (50)
Mirtazapine (15)
Valproic acid (400) | 4 | 0.25 | 27.3 | Increased appetite |
| | | | (Increased appetite) |
| | | |
| (3) BPII (M, 49) | Stage III | Amoxapine (75)
Milnacipran (100)
Sulpiride (150) | 12 | 3 | 87.5 | Orthostatic hypotension |
| | | |
| | | |
| (4) MDD (F, 41) | Stage III | Clomipramine (30)
Lithium (600) | 12 | 1 | 60.0 | Nausea |
| | | |
| (5) MDD (F, 38) |
Stage III | Clomipramine (75)
Sertraline (100) | 12 | 1 | 58.8 | Nausea |
| (6) MDD (M, 39) |
Stage III | 12 | 0.25 | 92.0 | None |
| (7) MDD, dysthymic disorder (F, 28) | Stage III | Milnacipran (50)
Aripiprazole (3) | 12 | 1 | 83.3 | None |
| | | |
| (8) BPII (F, 30) | Stage III | Milnacipran (75)
Aripiprazole (3)
Valproic acid (300)
Olanzapine (2.5) | 12 | 3 | 6.3 | Orthostatic hypotension |
| | | |
| | | |
| | | | |
| (9) MDD (M, 48) | Stage III | Duloxetine (20)
Mirtazapine (30)
Lithium (200)
Mianserin (30) | 12 | 2 | 41.2 | Drowsiness |
| | | |
| | | |
| | | |
| (10) MDD (M, 26) |
Stage II |
Paroxetine (40) | 8 | 3 | 55.6 | None (common cold) |
| (11) MDD (M, 32) | Stage III | Paroxetine (40)
Sulpiride (600) | 12 | 2 | 70.0 | Nausea |
| | | |
| (12) MDD, dysthymic disorder (M, 39) | Stage III | Paroxetine (40)
Milnacipran (25) | 12 | 3 | 17.4 | Drowsiness |
| | | |
| (13) MDD (F, 34) | Stage III | Clomipramine (150)
Lithium (400)
Sulpiride (150) | 12 | 2 | 90.0 | None |
| | | |
| | | |
| (14) MDD (F, 23) | Stage III | Amitriptyline (75)
Sertraline (100)
Valproic acid (400) | 12 | 1.125 | 71.4 | Agitation |
| | | | Insomnia |
| | | | Dry mouth |
| (15) BPII (F, 27) | Stage II | Mirtazapine (30)
Carbamazepine (100) | 12 | 1.5 | 31.3 | Drowsiness |
| | | |
| (16) MDD (F, 24) |
Stage I |
Sertraline (50) | 12 | 1 | 73.3 | None |
| (17) BPII (F, 40) | Stage III | Fluvoxamine (75)
Paroxetine (20)
Lithium (200) | 12 | 1.5 | 81.3 | None |
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