Table 2: Effect of MnTE-2-PyP on the activity of some enzymes of lung antioxidant defence system in mice asthma model.

28 day after treatment (48 hours after the last inhalation)

ParametersGroups
ControlOVAMnTE-2-PyPOVA + MnTE-2-PyP

SOD activity in U/g 3 1 . 1 ± 1 . 7 9 2 2 . 1 ± 1 . 9 4 * 2 8 . 6 ± 1 . 0 1 2 8 . 6 ± 1 . 2 5
mean ± SEM

CAT activity in mcat/g38.1429.48*35.9134.81
Median (min–max)(33.08–44.12)(21.51–31.20)31.92–38.7231.69–43.51
Q3–Q15.07 4.304.59.14

GP activity in U/g111.276.07*115.3101.5
Median (min–max)51.4–138.7466.85–83.56100.7–118.2562.27–136.92
Q3–Q129.656.3812.7449.81

NPSH groups in mol/g 10−7 0 . 5 8 ± 0 . 0 3 0 . 4 0 ± 0 . 0 3 * 0 . 5 4 ± 0 . 0 8 4 0 . 5 5 ± 0 . 0 4
mean ± SEM

OVA: ovalbumin; MnTE-2-PyP: Manganese (III) 5,10,15,20-tetrakis (N-ethylpyridinium-2-yl) porphyrin; SOD: superoxide dismutase; CAT: catalase; GP: glutathion peroxidase; NPSH groups: non protein sulfhydryl groups; SEM, standard error of mean; Q3–Q1: interquartile range
*Different from control at 𝑃 < 0 . 0 5 ;
Different from group 2 (OVA) at 𝑃 < 0 . 0 5 .