Gene Expression Profiles for Predicting Metastasis in Breast Cancer: A Cross-Study Comparison of Classification Methods

Figure 4

The procedure for external validation of classifiers. External classifier validation. Two datasets were used for training (AM and RO), and two others for testing (TR and MA). Datasets based on the Affymetrix and Agilent platforms are shown in orange and blue, respectively. RO and AM classifiers were used for evaluating external validation of classifiers developed from datasets using similar platform and using different microarray platforms, respectively. The models built in RO were tested in TR and MA and their mean performance calculated. This was done for all classification methods and compared. The same was done for testing AM models.