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| Sex | Age | Site | Medical history | D-dimer | Symptoms | Absolute size, cm | Histology | Intervention |
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Case 1 | F | 32 | great saphenous vein | none | 0.83 μg/mL | increasing respiratory distress and left thoracic pain | 3.1 × 2.9 | aneurysm venous wall with endothelial denudation, attenuation of the elastic lamellae and medial fibrosis in areas of thrombus adherence | Ligation/excision |
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Case 2 | M | 42 | popliteal vein | circulating phospholipid antibodies (aPL) | 0.94 μg/mL | acute shortness of breath | 3.2 × 3.6 | aneurysm venous wall characteristics with focal reduplication of the internal elastic lamina | tangential aneurysmectomy and lateral venorrhaphy |
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Case 3 | M | 43 | popliteal vein | hypertension | 1.21 μg/mL | acute shortness of breath not associated with pleuritic chest pain or hemoptysis | 2.9 × 3.6 | aneurysm venous wall with thickened, fibrotic, moderately cellular intima adjacent to a densely fibrotic adventitia and rare smooth muscle | resection of venous aneurysm with interposition autologous vein graft |
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Case 4 | M | 19 | cephalic vein | none | 0.42 μg/mL | increasing respiratory distress and right thoracic pain | | Aneurysm wall with fragmentation, and attenuation of the elastic lamellae, loss of smooth muscle cells, | Ligation/excision |
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Case 5 | M | 46 | small saphenous vein | Leg varicose vein, CAD | 0.63 μg/mL | acute shortness of breath | 2.6 × 2.3 | characteristics of varix | Ligation/excision |
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Case 6 | M | 42 | posterior tibial vein | none | 0.69 μg/mL | acute shortness of breath | 3.2 × 2.6 | attenuation of the elastic lamellae, loss of smooth muscle cells | tangential aneurysmectomy and lateral venorrhaphy |
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Case 7 | M | 42 | popliteal vein | circulating phospholipid antibodies (aPL) | 0.89 μg/mL | acute shortness of breath | 3.2 × 3.6 | aneurysm venous wall characteristics with focal reduplication of the internal elastic lamina | tangential aneurysmectomy and lateral venorrhaphy |
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Case 8 | M | 43 | popliteal vein | hypertension | 1.05 μg/mL | acute shortness of breath not associated with pleuritic chest pain or hemoptysis | 2.9 × 3.6 | aneurysm venous wall with thickened, fibrotic, moderately cellular intima adjacent to a densely fibrotic adventitia and rare smooth muscle | resection of venous aneurysm with interposition autologous vein graft |
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Case 9 | M | 19 | cephalic vein | none | 0.57 μg/mL | acute shortness of breath | | Aneurysm wall with fragmentation, and attenuation of the elastic lamellae, loss of smooth muscle cells, | Ligation/excision |
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Case 10 | M | 46 | small saphenous vein | Leg varicose vein, CAD | 0.71 μg/mL | increasing respiratory distress and right thoracic pain | 2.6 × 2.3 | characteristics of varix | Ligation/excision |
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Case 11 | M | 42 | popliteal vein | circulating phospholipid antibodies (aPL) | 0.82 μg/mL | acute shortness of breath | 3.2 × 3.6 | aneurysm venous wall characteristics with focal reduplication of the internal elastic lamina | tangential aneurysmectomy and lateral venorrhaphy |
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Case 12 | M | 43 | popliteal vein | hypertension | 1.32 μg/mL | acute shortness of breath not associated with pleuritic chest pain or hemoptysis | 2.9 × 3.6 | aneurysm venous wall with thickened, fibrotic, moderately cellular intima adjacent to a densely fibrotic adventitia and rare smooth muscle | resection of venous aneurysm with interposition autologous vein graft |
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