Table 1: Patient demographic and characteristic data.

SexAgeSiteMedical historyD-dimerSymptomsAbsolute size, cmHistologyIntervention

Case 1F32great saphenous veinnone0.83 μg/mLincreasing respiratory distress and left thoracic pain3.1 × 2.9aneurysm venous wall with endothelial denudation, attenuation of the elastic lamellae and medial fibrosis in areas of thrombus adherenceLigation/excision

Case 2M42popliteal veincirculating phospholipid antibodies (aPL)0.94 μg/mLacute shortness of breath3.2 × 3.6aneurysm venous wall characteristics with focal reduplication of the internal elastic laminatangential aneurysmectomy and lateral venorrhaphy

Case 3M43popliteal veinhypertension1.21 μg/mLacute shortness of breath not associated with pleuritic chest pain or hemoptysis2.9 × 3.6aneurysm venous wall with thickened, fibrotic, moderately cellular intima adjacent to a densely fibrotic adventitia and rare smooth muscleresection of venous aneurysm with interposition autologous vein graft

Case 4M19cephalic veinnone0.42 μg/mLincreasing respiratory distress and right thoracic pain 2 . 9 × 3 . 5 Aneurysm wall with fragmentation, and attenuation of the elastic lamellae, loss of smooth muscle cells,Ligation/excision

Case 5M46small saphenous veinLeg varicose vein, CAD0.63 μg/mLacute shortness of breath2.6 × 2.3characteristics of varixLigation/excision

Case 6M42posterior tibial veinnone0.69 μg/mLacute shortness of breath3.2 × 2.6attenuation of the elastic lamellae, loss of smooth muscle cellstangential aneurysmectomy and lateral venorrhaphy

Case 7M42popliteal veincirculating phospholipid antibodies (aPL)0.89 μg/mLacute shortness of breath3.2 × 3.6aneurysm venous wall characteristics with focal reduplication of the internal elastic laminatangential aneurysmectomy and lateral venorrhaphy

Case 8M43popliteal veinhypertension1.05 μg/mLacute shortness of breath not associated with pleuritic chest pain or hemoptysis2.9 × 3.6aneurysm venous wall with thickened, fibrotic, moderately cellular intima adjacent to a densely fibrotic adventitia and rare smooth muscleresection of venous aneurysm with interposition autologous vein graft

Case 9M19cephalic veinnone0.57 μg/mLacute shortness of breath 2 . 9 × 3 . 5 Aneurysm wall with fragmentation, and attenuation of the elastic lamellae, loss of smooth muscle cells,Ligation/excision

Case 10M46small saphenous veinLeg varicose vein, CAD0.71 μg/mLincreasing respiratory distress and right thoracic pain2.6 × 2.3characteristics of varixLigation/excision

Case 11M42popliteal veincirculating phospholipid antibodies (aPL)0.82 μg/mLacute shortness of breath3.2 × 3.6aneurysm venous wall characteristics with focal reduplication of the internal elastic laminatangential aneurysmectomy and lateral venorrhaphy

Case 12M43popliteal veinhypertension1.32 μg/mLacute shortness of breath not associated with pleuritic chest pain or hemoptysis2.9 × 3.6aneurysm venous wall with thickened, fibrotic, moderately cellular intima adjacent to a densely fibrotic adventitia and rare smooth muscleresection of venous aneurysm with interposition autologous vein graft

CAD: Coronary artery disease.