Antibiotic Resistance of Salmonella enterica Serovar Typhi in Kolkata, India, and In Vitro Experiments on Effect of Combined Chemotherapy

Table 1

Interaction of Cp (ciprofloxacin) in combination with G (gentamicin), trimethoprim (TMP), amoxicillin (Ax) and cefazolin (Cz) against S. enterica serovar Typhi isolates.

Antibiotic combination	MIC (μg/mL)	FIC (μg/mL)	FIC index
Cp-G	Cp: 0.75–1.25	Cp: 0.008–0.032	0.121–0.216
	GM: 0.75–2	GM: 0.1–0.2
Cp-TMP	Cp: 0.5–1	Cp: 0.025–0.125	0.14–0.483
	Tm: 10–125	Tm: 5–10
Cp-Ax	Cp: 1–1.25	Cp: 0.004–0.256	0.504–0.832
	Ax: 0.5–16	Ax: 0.25–10
Cp-Cz	Cp: 0.5–1.25	Cp: 0.075–0.25	0.35–0.916
	Cz: 2.5–60	Cz: 1.25–2.5

FIC: fractional inhibitory concentration; MIC: minimum inhibitory concentration.