MHC-unrestricted CD3(+) T-LGLs with TCR expressing KIRs [17].
B cells, T cells, NK cells
MHC-unrestricted CD3(ā) NK-LGLs without TCR, which may be positively triggered by circulating antibody against red-cell antigens activating NK-receptors and adhesion molecules [17].
Antibody cross-linking the TCR of the T-LGLs with the Fc receptor on target cells [19, 20].
Antibody cross-linking the Fc receptor on the T-LGLs or NK-LGLs (CD16) with any specific ligand for the antibody on the target cells [19, 20].