Table 1: Loci and genes associated with familial PD.

DesignationLocusGeneInheritance*Refs

Validated loci
PARK1/PARK44q21SNCAAD[516]
PARK812q12LRRK2AD
PARK26q25.2–q27PARKAR
PARK61p35-36PINK1AR
PARK71p36DJ-1AR
PARK91p36ATP13A2AR
Other loci
PARK32p13UnknownAD[1723]
PARK54p14UCH-L1AD
PARK812q12LRRK2AD
PARK101p32UnknownNot clear
PARK112q36-37GIGYF2AD
PARK12Xq21-q25UnknownX-linked
PARK132p12OMI/
HTRA2
AD
PARK 1422q13.1PLA2G6AR
PARK 1522q11.2-qterFBXO7AR

*AD: autosomal dominant; AR: autosomal recessive.