Table 1: Treatment scheme with group codes, doses and treatment times.

Group codeTreatment and dose

C33 weeks, untreated
VC33 weeks, distilled water, orally
MnL33 weeks 14.84 mg/kg b.w. MnCl2, orally
MnH33 weeks 59.36 mg/kg b.w. MnCl2, orally
C336 weeks, untreated*
VC333 weeks, distilled water, orally + 3 weeks HEC intratracheally
MnL333 weeks 14.48 mg/b.w. kg MnCL2, orally + 3 weeks MnO2 NPs 2.63 mg/kg b.w. intratracheally
MnH333 weeks 59.36 mg/b.w. kg MnCL2, orally + 3 weeks MnO2 NPs 2.63 mg/kg b.w. intratracheally
C66 weeks, untreated*
VC66 weeks, distilled water, orally
MnL66 weeks 14.84 mg/kg b.w. MnCl2, orally
MnH66 weeks 59.36 mg/kg b.w. MnCl2, orally

*C33 and C6 were two different groups of rats.