Table 2: (a) OR (95% CI) for incidence of leukoaraiosis. (b) OR (95% CI) for severity of white-matter lesions.

Multivariate logistic regression analysis (a) OR (95% CI) (b) OR (95% CI) Adjusted for gender, BMI, ever smoking, hypertension, diabetes mellitus, hyperlipidemia, medication use, acetylsalicylic acid, clopidogrel, beta blockers, calcium blockers, ACE inhibitors, ARBs, HMG-CoA reductase inhibitors, stroke history, stroke etiology for Leukoaraiosis occurrence for severity of white matter lesions Age, years 1.043 (1.012–1.075), 1.065 (1.027–1.103), IMT above median (0.65 mm) 2.503 (1.181–5.302), 3.012 (1.315–6.897),

OR indicates odds ratio; CI: confidence interval; BMI: body mass index; ACE: angiotensin converting enzyme; ARB: angiotensin receptor blockers; HMG-CoA, 3-hydroxy-3-methylglutaryl-Coenzyme A; IMT: intima-media thickness.