Table 2: (a) OR (95% CI) for incidence of leukoaraiosis. (b) OR (95% CI) for severity of white-matter lesions.

                                                      Multivariate logistic regression analysis
(a) OR (95% CI)(b) OR (95% CI)

Adjusted for gender, BMI, ever smoking, hypertension, diabetes mellitus, hyperlipidemia, medication use, acetylsalicylic acid, clopidogrel, beta blockers, calcium blockers, ACE inhibitors, ARBs, HMG-CoA reductase inhibitors, stroke history, stroke etiologyfor Leukoaraiosis occurrencefor severity of white matter lesions
Age, years1.043 (1.012–1.075), 𝑃 = 0 . 0 0 6 1.065 (1.027–1.103), 𝑃 = 0 . 0 0 1
IMT above median (0.65 mm)2.503 (1.181–5.302), 𝑃 = 0 . 0 1 7 3.012 (1.315–6.897), 𝑃 = 0 . 0 0 9

OR indicates odds ratio; CI: confidence interval; BMI: body mass index; ACE: angiotensin converting enzyme; ARB: angiotensin receptor blockers; HMG-CoA, 3-hydroxy-3-methylglutaryl-Coenzyme A; IMT: intima-media thickness.