Clinical Study

Leukoaraiosis Is a Chronic Atherosclerotic Disease

Table 3

Risk factors and carotid ultrasonography characteristics by severity of WMCs.

           Advanced WMCs
NoYes 𝑃 -value
( 𝑛 = 1 2 1 )( 𝑛 = 4 9 )

Age, years63.6 ± 13.473.1 ± 10.8<0.001
Male gender62.059.20.734
BMI, kg/m227.1 ± 4.626.4 ± 4.10.373
Diabetes mellitus, %26.432.70.415
Hypertension, %57.077.10.015
Hyperlipidemia, %46.347.90.848
Current smoker, %29.119.10.192
Ever smoker, %56.852.10.581
Mean IMT*, mm0.81 ± 1.120.87 ± 1.130.003
Carotid plaque/s, %64.987.50.004
Within Lacunar strokes, %68.531.50.834

WMC indicates white matter changes; IMT: intima-media thickness.
*Data were logarithmically transformed before analysis, presented is the geometric mean (SD).