Expressions of MMPs and TIMP-1 in Gastric Ulcers May Differentiate H. pylori-Infected from NSAID-Related Ulcers

Table 1

Demographic and clinical characteristics of the three gastric ulcer groups.

Ulcer groups
Parameters	H. pylori infected (𝑛=46)	NSAID related (𝑛=30)	Combined H. pylori infection and NSAID use (𝑛=50)	P value
Mean age (years)	62.2 (16.6)	64.1 (14.4)	69.2 (13.1)	0.06^†
Women (%)	23.9	56.7	44.0	0.01^‡
Size of ulcer (cm)	1.4 (1.0)	1.3 (1.1)	1.7 (1.5)	0.20^†
Number of ulcers (𝑛), single : multiple	18 : 28	7 : 23	12 : 38	0.19^‡
Ulcer locations (𝑛) antrum : corpus : both	21 : 16 : 9	21 : 1 : 8	33 : 4 : 13	0.002^‡
Hemoglobin (g/dL)	10.9 (2.8)	9.5 (2.9)	10.1 (2.9)	0.13^†
Albumin (g/dL)	3.5 (0.8)	3.7 (0.8)	3.5 (0.6)	0.60^†
Creatinine (mg/dL)	1.5 (1.6)	1.6 (1.9)	1.3 (1.1)	0.69^†

^†Mean (SD or standard deviation), by one-way ANOVA test.
^‡The chi-square test. Normal range, Hemoglobin 13.5–17 g/dL; Albumin 3–5 g/dL; Creatinine 0.7–1.5 mg/dL.
H. pylori: Helicobacter pylori; NSAID: Nonsteroidal anti-inflammatory drugs.