Clinical Study

Central Precocious Puberty: Treatment with Triptorelin 11.25 mg

Table 1

Clinical data at the beginning of GnRH analog treatment (M0) and after 12 months of quarterly triptorelin 11.25 mg (M12).

M0M12

Bone age, years 9 . 8 ± 1 . 2 1 0 . 7 ± 1 . 1
Height, cm 1 3 2 . 7 ± 7 . 8 1 3 9 . 1 ± 8 . 6
Height, SDS* 0 . 4 ± 1 . 3 0 . 3 ± 0 . 9
Growth velocity, cm/year 1 1 . 0 ± 4 . 9 4 . 9 ± 2 . 1
Predicted adult height, cm 1 5 6 . 3 ± 9 . 6 1 6 0 . 8 ± 6 . 5
Predicted adult Height, SDS 0 . 7 ± 1 . 5 0 . 2 ± 1 . 1
Body mass index, kg/m2 1 8 . 0 ± 2 . 5 1 8 . 6 ± 2 . 4
Body mass index, SDS 2 . 8 ± 2 . 7 2 . 7 ± 2 . 0
Midparental height, cm 1 6 1 . 0 ± 4 . 5
Midparental height, SDS 0 . 2 ± 0 . 8

*SDS for bone age; 𝑃 < 0 . 0 2 versus M0; 𝑃 < 0 . 0 0 1 versus M0.