Clinical Study

Central Precocious Puberty: Treatment with Triptorelin 11.25 mg

Table 2

Biochemical data at baseline and 3, 6, and 12 months of quarterly triptorelin 11.25 mg.

baseline3 months6 months12 months

Basal LH,  IU/L 1 . 9 ± 1 . 6 0 . 3 ± 0 . 2 0 . 4 ± 0 . 4 0 . 4 ± 0 . 2
Peak LH,  IU/L 2 5 . 7 ± 1 6 . 5 0 . 9 ± 0 . 5 1 . 0 ± 0 . 5 1 . 0 ± 0 . 5
Peak LH < 3 IU/L17/1717/1717/17
Basal FSH,  IU/L 4 . 1 ± 2 . 2 0 . 9 ± 0 . 5 1 . 1 ± 0 . 5 1 . 5 ± 0 . 8
Peak FSH,  IU/L 1 1 . 7 ± 4 . 7 1 . 3 ± 0 . 6 1 . 3 ± 0 . 6 1 . 9 ± 0 . 9
17β estradiol, pmol/L° 5 8 . 0 ± 4 5 . 5 3 0 . 8 ± 7 . 7 2 7 . 8 ± 1 2 . 1 3 4 . 1 ± 1 2 . 1
17β estradiol < 70 pmol/L°11/1616/1616/1616/16

°data related to the 16 girls enrolled in the study. °Peak < 2 IU/L 17/47 a M3, M6, M12.