Table 3: Test conditions to optimize.

Profile analyzedSelected variable

Drug releaseTime to release 50 percent of entrapment drug ( 𝑡 5 0 % )
Area under curve (AUC)
Entrapment efficiencyEntrapment efficiency (EE)
Swelling performanceSwelling rate (SR)
Shape of the particlesShape factor (SF)
Size of the particlesMean diameter (Dm)